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Summary Respiratory papillomatosis pathology outlines Insulinemia joacã un rol cheie în dezvoltarea leziunilor de acanthosis negricans. Summary Acanthosis nigricans is consdered to be respiratory papillomatosis pathology outlines a marker of insulin-resistance and secondarily a marker of a subclinical malignant process. The serum level of insulin plays a key role in the development of AN lesions. When it reaches respiratory papillomatosis pathology outlines beyond respiratory papillomatosis pathology outlines, insulin binds preferentially to IGF insulin-like growth factor and becomes the trigger for epidermal and dermal proliferation.
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La valori peste normal insulina se leagã preferenþial de receptorii IGF insuliln-like growth factor ºi devine trigger-ul pentru hiperproliferare dermoepidermicã. Summary Acanthosis nigricans is consdered to be primarly a marker of insulin-resistance and secondarily a marker of a subclinical malignant process.
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